Pionus detects, segments and quantifies every hypermetabolic foci in FDG PET/CT examinations. It highlights every anomaly with a clear contour and provides the standard quantification used in a nuclear medicine report. Pionus serves as a safeguard to avoid errors, increases efficiency, and computes essential biomarkers for metabolic activity in clinical routines including Total metabolic Tumor Volume (TMTV) and Total Lesion Glycolysis (TLG).